Luis Enrique's Barcelona made it 28 games in a row without defeat, while Real Madrid snatched a win against Granada and Valencia lost again.
Paris Saint-Germain are 24 points clear in Ligue 1 following a 2-1 win at Marseille but coach Laurent Blanc is not entirely happy.
Zlatan Ibrahimovic and Angel Di Maria scored to give an unconvincing PSG side their ninth successive Le Classique victory over Marseille.
Chelsea boss Guus Hiddink was relieved to see his side grab a deserved point against Manchester United at Stamford Bridge.
Luka Modric scored a stunning winner for Real Madrid against Granada and Zinedine Zidane wants to see more such efforts in future.
Juan Cuadrado and Paulo Dybala scored to give Juventus a 2-0 win at Frosinone and keep the Old Lady two points behind table-topping Napoli.
Argentine midfielder Angel Di Maria's ninth league goal of the season helped Paris Saint-Germain to a ninth successive win over Marseille.
Luka Modric scored a stunning winner as Real Madrid beat Granada 2-1 in a hard-fought La Liga clash at Los Carmenes.
Hoffenheim fell to a poor defeat at home to Darmstadt, while Hamburg and Cologne played out a draw in the Bundesliga.
Following Manchester United's draw with Chelsea, Louis van Gaal was unimpressed with questions over his future at the club.
Chelsea's Kurt Zouma suffered what appeared to be a serious knee injury against Manchester United and will undergo medical examinations.
Former Liverpool manager Brendan Rodgers knows about working under Fenway Sports Group and he has advice for his old employers.
Diego Costa denied Manchester United a win over Chelsea with a late goal and Louis van Gaal was angry that his side could not hold on.
Maurizio Sarri says Napoli will treat their top-of-the-table Serie A clash with Juventus like any other game.
Despite Chelsea claiming the door was still open for John Terry to sign a new contract, the captain stated there are no ongoing talks.
Chelsea snatched a late equaliser to draw 1-1 with Manchester United and Jesse Lingard admitted his side felt like they had lost.
Leicester City hold a five-point lead at the Premier League summit but Sol Campbell is unsure how they will handle the pressure.
Juventus will be ready for the visit of Napoli next week as Serie A's top two go head-to-head in Turin, says Massimiliano Allegri.
Guus Hiddink remains unbeaten in his second spell as Chelsea boss after a 1-1 draw with Manchester United that saw Kurt Zouma injured.
Arsene Wenger says only a win will do when Arsenal take on Premier League title rivals Leicester City next week.